Press releases


December 2019 · Pluristem
Pluristem Completes 75% Enrollment in its Pivotal Phase III CLI Clinical Study
Patients unsuitable for revascularization surgery currently have no alternative treatments, leading to high risk of leg amputation and death; PLX-PAD may become the first drug approved to treat CLI.
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May 2019 · Pluristem
Lead Physicians in Pluristem’s Pivotal Study in Critical Limb Ischemia Publish Peer-Reviewed Paper
Paper appears in the European Journal of Vascular and Endovascular Surgery and highlights the study’s design rationale and the potential impact of PLX cells in the treatment of CLI.
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April 2019 · Pluristem
Pluristem Completes Interim Enrollment in Pivotal CLI Study, Targeting Potential Conditional Marketing Approval in Europe
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December 2018 · Pluristem
Pluristem Therapeutics Recaps Key Opinion Leader Meeting on Peripheral Artery Disease (PAD)
Presentations underscore significant need for new PAD treatment approaches and the potential of cell therapy to improve patient outcomes while reducing healthcare costs.
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August 2018 · Pluristem
Pluristem Initiates Two Pivotal Phase III Studies in Israel
Numerous Clinical Sites in Israel to join sites in the U.S. and Europe for Pivotal Phase III Studies of PLX-PAD Cell Therapy in the Treatment of Critical Limb Ischemia and Muscle Injury Following Hip Fracture.
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June 2018 · Pluristem
Pluristem Reports Positive Top-Line Results from Its Multinational Phase II Intermittent Claudication Study
The IC study validates the design of our ongoing PACE phase III trial on Critical Limb Ischemia (CLI). Best results in the IC trial were obtain with two times administration of 300 million PLX-PAD cells. The same dosing is foreseen within PACE clinical study. Besides Pluristem, also other partners of the PACE consortium were involved in the IC trial as scientists: Sigrid Nikol (Asklepios) and Norbert Weiss (TUD) as lead principal investigator.
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February 2018 · Jerusalem Post · Sigrid Nikol
Smart cells that heal
Innovative Israeli cell therapy could step up treatment of CLI.
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February 2018 · LINC TODAY · Sigrid Nikol
Stem cell angiogenesis: showing promise
Pioneering techniques for critical limb ischaemia and "no option patients".
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July 2017 · Pluristem
Pluristem Advances its Multinational Phase III Critical Limb Ischemia Study, Targeting Initiation at 40 Active Sites
by the End of 2017
Austria’s regulatory health agency clears CLI study and joins the U.S., U.K., and Germany in conducting the 250-patient Phase III trial.
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January 2017 · Pluristem
Pluristem’s Phase III Study of PLX-PAD Cells for the Treatment of Critical Limb Ischemia Cleared by U.S. FDA
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